Wade will flirt with pretty about everything that moves. Gerry Duggan, the writer of Marvel NOW, has even stated that he will tackle “anything with a pulse.” Not only has he been turned on by men and women, but also by androids, aliens, and demons! ¹⁾

Deadpool embarks on a killing spree after becoming even more psychotic in the appropriately titled “Deadpool Kills the Marvel Universe”. During his fury, he virtually eliminates Marvel's whole roster. ²⁾

Patient Zero produced Itsy Bitsy (yep, like the nursery rhyme) by injecting a patient with Spidey and D-DNA. Pool's But, unlike her parents, Itsy Bitsy grew out to be bloodthirsty, with a cruel sense of humour and lethal web-shooting abilities. ³⁾

Wade referred to the actor in Deadpool and Cable #2. Deadpool has been characterized as “Ryan Reynolds crossed with a Shar-Pei”. That clearly started something, since it's almost as if Ryan Reynolds was born to portray Deadpool.⁴⁾